Tank bots are enemies in Up Your Arsenal. Only two are encountered, one in the challenge "Meet Courtney - Gauntlet" (renamed to "BBQ Boulevard" on replays) on the Annihilation Nation, and one during the mission "Find Dr. Nefarious" alongside the tyhrranoids. The tank bots are imposing, heavily armored vehicles that hover from the ground, and fire rockets or a short flamethrower.
Tank bots have tough armor and long-range, though each of their missiles can be dodged. One strategy is to simply stand retreat outside of their range where they cannot target Ratchet, and destroy them with powerful ranged weapons such as the Flux Rifle, Annihilator, or Disc Blade Gun.